Kidney Function May Affect Warfarin Dose
A new study published in the Journal of American Society of Nephrology shows that patients with decreased kidney function (kidneys not working normally) may be at increased risk for bleeding and may benefit from lower doses of warfarin (Coumadin, Jantoven). For more information please visit: http://jasn.asnjournals.org/cgi/content/abstract/20/4/912
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Update on the Risk of Breast Cancer with Hormone Replacement Therapy
Two recently published articles better describe the link between hormone replacement therapy (HRT) and risk of breast cancer. First, the increased risk of breast cancer occurs within 2 to 3 years of beginning hormone replacement therapy. Second, the risk of getting breast cancer decreases after you stop taking hormone replacement therapy. Hormone replacement therapy medicines include conjugated estrogens (Premarin), estradiol (Estrace, Climara, Vivelle and others), medroxyprogesterone (Provera, Cycrin), combination conjugated estrogens with medroxyprogesterone (Prempro, Premphase), and other progestins (progesterone, hydroxyprogesterone). For more information please visit: http://www3.interscience.wiley.com/journal/121645248/abstract and http://content.nejm.org/cgi/content/abstract/360/6/573
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