Safety Alerts & Recalls

What does this mean?

Canagliflozin is an important medicine for controlling Type 2 diabetes. You should continue to take your diabetes medicine as directed by your healthcare provider. This alert is a good reminder to regularly review the benefits and risks of your medicine with your healthcare provider.

You should notify your healthcare provider right away if you develop new pain or tenderness, sores or ulcers, or infections in your legs or feet. Talk to your healthcare provider if you have questions or concerns about canagliflozin or any of your medicines. Do not stop taking your diabetes medicine without first talking to your health care professional.

Increased Risk of Foot and Leg Amputations with Canagliflozin (Invokana, Invokamet, Invokamet XR)

Based on new data from two large clinical trials, the U.S. Food and Drug Administration (FDA) has concluded that the type 2 diabetes medicine canagliflozin (Invokana, Invokamet, Invokamet XR) causes an increased risk of leg and foot amputations. The prescribing information for all canagliflozin -containing medicines will be updated with this new information, including the FDA's strongest warning called a "Boxed Warning".

For more information, please visit: more information here

Source: FDA
Publication Date: 2017-07-31
Last Updated: 2017-07-31

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